MARK: "She told you. I've known you my whole life, I grew up with you so I know what you're thinking. That there is a year of your life wasted. Trying to make it work with Addison and you could have been with Meredith. That you could be happy right now. That all of this, everything... that you and Meredith could have had a real chance. Still, I thought you should know the truth. I thought I owed you that, as a friend."
DEREK: [walks away] "You're not my friend."


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Episode: Oh, The Guilt

Characters: Derek Shepherd, Mark Sloan

Cast: Patrick Dempsey, Eric Dane

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