Grey's Anatomy Spoilers (Page 3)

Here's a little Grey's Anatomy spoiler tidbit from E! Online's Q&A today. Okay, so we already knew this thanks to previous comments from Chandra Wilson, but here goes anyway:

Q: Waiting with bated breath for the Grey's Anatomy finale. Spill!

A: As Chandra Wilson said, "In [the finale], we do ultimately find out what [happens with] George (T.R. Knight) - he does make a big decision in that episode. Izzie has a lot of medical [issues] in that episode. And then we have our normal ER catastrophe that goes on. It has to be something bad going on where all the doctors have to assemble. That much I know."

Below are three more sneak previews of the 100th episode of Grey's Anatomy Thursday, "What a Difference a Day Makes." In the first, Mark and Meredith talk about the wedding in mid-surgery. Sloan "warns" her that he doesn't want to be Derek's best man a third time ...

What a Difference a Day Makes Sneak Preview #3

Follow the jump for two more clips from the episode that have nothing to do with the wedding, but do show George O'Malley in action as a trauma patient is rushed to the ER ...

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Jeffrey Dean Morgan confirms what the sneak previews of "What a Difference a Day Makes" have already shown - that he will reprise his role as Denny on Grey's Anatomy once again in this fifth season. But then that's it, he insists. Really.

"I can confirm that I will be coming back one more time," he revealed to EW at last weekend's Hollywood premiere of Star Trek. "I think it will be done after that. I think that I have officially been on the Grey's Anatomy set for the last time."

Morgan wouldn't comment on when exactly Denny turns up, but we know he will reappear as a figment of Izzie's cancer-ravaged imagination in Thursday's 100th episode.

"Denny has a reason to show up," Morgan teased.

"And it's probably tied to Izzie's health."

Given the number of times Denny has returned to Grey's Anatomy since he died in the epic Season 2 finale three years ago, Morgan states the obvious when he says:

"I think they're regretting killing me off a little bit. But it's done and it's been great. I love those people. Shonda Rhimes gave me the opportunity of a lifetime."

What do you think brings Denny back? Will you be sad to see him go?

Our favorite show's 99th installment last night was terrific. Below is a sneak preview for next week's landmark 100th episode of Grey's Anatomy, "What a Difference a Day Makes."

It's the day of Meredith and Derek's wedding and the bride-to-be is feeling a bit nervous about what's to come. Her maid of honor isn't exactly helping calm her nerves ...

What a Difference a Day Makes Sneak Preview #1

Follow the jump for the 30-second promo that aired after last night's show, as well as another sneak preview of the episode featuring the wedding-obsessed Izzie Stevens.

After begging Bailey to let her attend the big event in spite of her deteriorating condition, Izzie starts to experience some familiar symptoms. Handsomely familiar ...

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Michael Ausiello of Entertainment Weekly has some quality Grey's Anatomy spoilers and gossip in his weekly Q&A today. Give this a read and then comment away ...

Q: Is there any news as to whether Jessica Capshaw will be back on Grey's Anatomy next season?

A: Not only will she be back, she's finalizing a deal to become a full-fledged series regular! Holla if you're a lesbian!

Q: Will Meredith and Thatcher finally resolve their issues on Grey's Anatomy?

A: Not exactly. She, will, however reach a new understanding with the Chief. She even gives him a gift. A pretty major gift. A gift I have a hunch will play a big role next season (if the story is going where I think it's going).

Q: Can you give me some Grey's Anatomy scoop about Mer-Der? I'm tired of hearing about Izzie!

A: You're in luck! Sharon Lawrence, who guest stars this week as Izzie's trailer-trash mom, had some interesting things to say about working alongside Katherine Heigl...

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As if Izzie's cancer, Mer and Der's wedding and George actually getting a storyline weren't enough for the season finale of Grey's Anatomy, Chandra Wilson says there is still a medical disaster that will call for all hands on deck at Seattle Grace.

At the Prism Awards this weekend, Chandra teased the life-changing finale, painting a picture of what could well to be the most thrilling Grey's Anatomy season-ender yet.

"In [the finale], we do ultimately find out what [happens with] George - he has to make a very big decision. Izzie has a lot of medical [issues] in that episode," she said.

"And then, of course, we have our normal ER catastrophe that goes on. It's got to be something bad going on where all the doctors have to assemble. That much I know."

Speaking of George's big decision, there's a rumor he ends up as a trauma surgeon in the army, following in Owen Hunt's footsteps. "Is that right? That's coming up too? Lord, I need to read the script that you're reading!" jokes Chandra Wilson.

While she is tight-lipped on the rest of the season, she says Bailey is prepared to continue with pediatric surgery despite the ramifications it has for her marriage:

"Everything that I'm doing right now is still working with the kids; it's still trying to potentially go into that fellowship. I do know that my husband is not happy about that. But when you get a calling, sometimes you have to do your calling."

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How will the return of Thatcher Grey (Jeff Perry) in this week's episode play out for Meredith and Lexie, who just endured the feuding of their significant others last week?

Check out this excerpt from TV Guide's spoiler Q&A today and see what you think ...

Q: I adored all of the "McFamily" scenes last week on Grey's Anatomy. What's next for Mark, Lexie, Meredith and Derek?

A: For Mark and Lexie, much cuteness is on the immediate horizon. I mean, as much as Thatcher Grey makes my skin crawl, the way things play out when he returns is better than I expected.

For Mer and Der, there's the none-too-small matter of a stern ultimatum coming from the bride. As that gets sorted out, the would-be marrieds will find cause to fast-track their wedding, so get to updating that website, Izzie!

As teased in yesterday's promo, Seattle Grace admits a patient unlike any it has seen before this week - a victim of a shooting, perpetrated by a small child. That's a new one for sure.

Will George step up to the plate? How will the case spark a feud between Mer and the Chief? Take a look at this preview of "No Good at Saying Sorry" and tell us what you think:

No Good at Saying Sorry Sneak Preview

Below are some Grey's Anatomy spoilers from E! Online's weekly Q&A this morning. Here's the latest on how Izzie's doing - at least according to her mom - and what's going down between Meredith and the Chief. Spoiler alert: it could get ugly!

Q: How's Izzie doing on Grey's Anatomy?

A: Sharon Lawrence makes her debut as Izzie's mother this week, and according to Izzie's mother's psychic, Izzie is going to be just fine. You will be shocked to learn Izzie's mother's psychic is not reliable, and in point of fact, Izzie's cancer is getting worse, not better.

Q: Any scoop for this week's episode of Grey's Anatomy?

A: Meredith steps over the line with a patient this week, and that causes the fight of the century between her and the Chief. She also un-invites him from the wedding!

On a side note, if you haven't seen it, you can check out Mer and Der's official wedding website if you are looking for more details about the special day.

Below is a promo for this Thursday's all-new episode of Grey's Anatomy, "No Good at Saying Sorry (One More Chance)." It's the 21st episode of the current fifth season.

Check out our photo gallery from the episode for more of an idea of what's to come, then take a look at the clip below and comment away. Sneak peeks still to come!

No Good at Saying Sorry Promo