Justin Chambers
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We may have seen the last of the talented T.R. Knight on Grey's Anatomy, following this week's sad announcement that accounts of his leaving the series are official.

But at least we still have Justin Chambers.

Here, the 38-year-old who plays Alex, a father of five, is seen enjoying some rest and relaxation in Hawaii, where he's on a nice vacation with his wife, Keisha Chambers:

Justin Chambers enjoys down time in between Grey's Anatomy seasons.

Is he staying? Is he going?

The debate goes on (and on, and on). But you can count Justin Chambers among those who don't want T.R. Knight to leave the cast of Grey's Anatomy.

"T.R. is an amazing actor and I want him to be there as long as I'm on there," said Chambers, who plays Dr. Alex Karev on Grey's Anatomy, to E! Online the other night at the Salvatore Ferragamo benefit for L'Aquila Earthquake victims. "He's wonderful to work with."

Besides, T.R.'s character, Dr. George O'Malley, has so much growing to do.

"That's one of the great things about the show," Justin Chambers said.

"All the characters have so much left to explore. From the beginning of the series, the audience followed these young interns coming into this hospital and now they're residents ... but they still have much more to learn as far as surgery, social skills and manners."

For her part, former Grey's Anatomy guest star Melissa George said she's not convinced that Knight is leaving the show he's been on since its 2005 premiere.

No matter what happens, she said, "He'll go on to bigger and better things."

Grey's Anatomy star Justin Chambers conducted several interviews on the talk show circuit this week, teasing tonight's big 100th episode and the following week's season finale.

Check out the hunky star on The View and Good Morning America below ...

If you’re not a fan of Grey's Anatomy spoilers, avert your eyes. But if you’re down with knowing the details and truth directly from the actors, then read on!

Izzie’s (Katherine Heigl) condition is solved by the interns in the next Grey's Anatomy (the March 12 episode), according to Justin Chambers (Alex Karev).

“Izzie has cancer, so I’m there to support her,” he tells TV Guide.

There you go.

With all the trials and tribulations that have befallen Izzie Stevens lately - the return of the ghost of Denny Duquette, sex with the ghost of Denny Duquette, making crafts for her team of interns - this probably doesn’t come as a major surprise.

But to actually hear the word “cancer” from Justin Chambers, who plays her love interest, confirms what viewers probably knew for months sensed was coming.

The actor says that Alex and the rest of the Seattle Grace gang are going to have their hands full as they help their friend Izzie deal with her upcoming battle.

“I would expect Alex to shut down a little bit if something awful happens to Izzie, but these are opportunities to see his chivalrous side and his true love for her, so there should be some interesting stuff coming up,” says Chambers.

Katherine Heigl greeted Grey's Anatomy co-star and sort-of on-screen boyfriend Justin Chambers at her 30th birthday dinner at L.A.'s Rose restaurant Monday.

Both are happily married to others, of course (Katherine to singer Josh Kelley and Justin to former modeling agent Keisha, with whom he has five children), but it's always neat to see our favorite cast members hanging out as friends together off the set ...

Grey's Anatomy stars Ellen Pompeo and Justin Chambers attended a fundraiser sponsored by the Gay and Lesbian Leadership Council of the Democratic Committee (GLLC) in Seattle this weekend for Presidential hopeful and U.S. Sen. Barack Obama.

Ellen Pompeo talked about her heritage and wanting to bring the U.S. back to the ideals embraced by her Italian-American ancestors. She acknowledged that being a celebrity campaigning for candidates and causes makes some people - herself included - a bit uncomfortable, but feels strongly about this one.

She also told the gay audience about her two gay uncles and how happy she is that they can marry in her native Massachusetts after all this time. California has since legalized gay marriage as well, prompting rumors that Ellen's Grey's Anatomy co-star T.R. Knight may wed soon (he says don't hold your breath).

Justin Chambers then gave brief remarks about being the father of five children and his increasing concern for the world now and in his children’s future.

Regardless of how you feel about Barack Obama, it's always nice to get some Ellen Pompeo news, as she generally stays pretty clear of the limelight.

NOTE: We were sent this photo by a reader - if anyone knows where we can find more (or better) pics, we'll gladly post them with appropriate credit(s).

Grey's Anatomy stars Ellen Pompeo and Justin Chambers are stepping out to show support for their presidential candidate of choice.

You’re also invited, if you support Sen. Barack Obama.

The Gay and Lesbian Leadership Council of the Democratic National Committee cordially invites you to a night of cocktails, hors d’oeuvres and political chatter with Ellen Pompeo and Justin Chambers of Grey's Anatomy.

Proceeds go toward benefiting the Obama Victory Fund. Private Practice star Kate Walsh is also a huge supporter, though not participating in this event.

The event will be held in Seattle, Washington on August 16. For additional information, check out the candidate's website for more details ...

You're welcome, again ...

Grey's Anatomy star Justin Chambers is just too hot for words.

Paging Dr. Karev! Grey's Anatomy star Justin Chambers paid visit to the Pilgrim School in the Korea Town section of L.A. on Wednesday morning.

Justin, who has been going through tough times lately, appeared to be in good spirits once again, meeting wife Keisha and picking up their kids.

REGULAR DAD: Justin Chambers, who was so terrific as Dr. Alex Karev in "Freedom," the season finale of Grey's Anatomy, picks his kids up from school.

The Pilgrim School is a (non-denominational) division of the First Congregational Church of L.A. One hundred percent of graduates go on to seek higher education.

Grey's Anatomy star Justin Chambers is finally doing better.

"I'm doing really good â€" I'm actually sleeping!" Chambers, 37, who plays Dr. Alex Karev on the ABC hit, told a reporter at the kick-off party for the Butterfly Ball Tuesday at Saks Fifth Avenue in Beverly Hills.

In January, Chambers voluntarily checked himself in at UCLA Medical Center to get help with a pre-existing sleeping disorder for three days.

These days, "I am really enjoying life," the Grey's Anatomy actor said.

What's helping Justin Chambers (with wife Keisha) settle his life down?

Bikram yoga, which he's been doing for the past two months.

"It is where you sit in a 104-degree room, and you stretch for an hour-and-a- half," he explained. "I swear by it â€" it's incredible."

His wife Keisha Chambers â€" with whom he has five kids â€" has also been a source of support.

"We are going on 14 years," Justin Chambers said. "When we get to 50, we will send you a postcard!"