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Kaley Cuoco to Guest Star on Grey's Anatomy

A big (bang) guest star has signed on for the Grey's Anatomy season finale.

According to Michael Ausiello, a CBS sitcom star has signed on to appear in the the May 14 episode.

Kaley Cuoco, the lovely leading lady on The Big Bang Theory, will star in the finale as... someone. The actress admits she actually has no idea about the character she'll portray.

"I am working on Grey's Anatomy next week," Cuoco said. "It is a big ol' secret. I have no clue what I am doing. I swear on my life that I have no idea what I am playing because it is the finale and they are keeping it under wraps until the last possible moment."

Kaley Cuoco

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40 Comments

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  1. Megan Says:

    hmm, if she was a patient, I doubt they'd be so secretive about it. Maybe she's got something to do with the wedding (an old friend of Izzie's perhaps? That's if it's actually an Alex/Izzie wedding...)

  2. bren Says:

    alex's sister!!!

  3. Ashlee Says:

    I love kaley! cant wait for this episode :)

  4. Nina Says:

    She's from Charmed!

  5. 8anos Says:

    Oh my God! A star from Charmed in Grey's?! My two favorite shows together! Now THIS is what I call blessing! What's next? Ohh I know...maybe a demon will be admitted to the hospital because Piper kicked his ass!

  6. Josefine Says:

    That´s gonna be so much fun!!!

  7. marriedmymcdreamy Says:

    Yay! Big Bang Theory is my favorite comedy. My two favorite shows are colliding!

  8. Terrance J Says:

    Maybe she is Izzie's half sister. Theory - Through surgeries the team at Seattle Grace will remove all signs of cancer; succesfully putting Izzie into remission. Once there they will decide that her only chance for a future will be to undergo a stem cell transplant. The long lost step sister will be a match and become the stem cell donor for Izzie.

  9. DJ Says:

    I think she will play Izzie's child.

  10. EILEEN Says:

    she's too old to be Izzie's child!!!

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