As we reported last week, the lovely Kaley Cuoco was set to guest star on Grey's Anatomy, only to suddenly disappear from the cast a few days ago.
Well, EW has cracked the case of the mysterious vanishing guest star.
Although the actress' rep says an unforeseen "publicity commitment" forced The Big Bang Theory star to back out of a top-secret appearance on Grey's Anatomy's May 14 season finale, multiple sources say it was her current employer, CBS, that nixed the deal.
An CBS spokesperson couldn't be reached for comment, but one insider explains, "They didn't want one of their biggest stars appearing on one of ABC's biggest shows."

As a result, Grey's Anatomy has instead tapped former OC starlet Shannon Lucio (she played Caleb's illegitimate daughter, Lindsay) to fill Kaley Cuoco's shoes.
Still unknown: Who the heck is she playing?
Some speculated that, based on Cuoco's resemblance to Grey's Anatomy star Katherine Heigl, perhaps the character is a relative of Izzie Stevens.
That possibility may be less likely with the casting of Lucio... or is it?



April 24th, 2009 10:20 AM
Damn, I was looking so forward to seeing Kaley Cuoco on Grey's. Sad! Silly CBS!!!!
April 24th, 2009 12:10 PM
Didn't Lexie has a sister? Maybe she is playinr her.
April 24th, 2009 2:10 PM
She is definitely not playing Lexie's sister, Molly, because we saw Molly in season 3 when she gave birth to her daughter, and Addison had to perform multiple surgeries on the baby, it was when Mer had the snoring issue, those epis.
So, she is definitely not playing Molly.
April 24th, 2009 3:08 PM
There was another sister talked about though. Could be her. Could be a relative of Izzie too. Could be anyone really, you never know what curve Shonda is going to throw us! That's why we love it so much!
April 24th, 2009 5:37 PM
No, only 3 sisters. Meredith, Lexie and Molly.
I was soooooooooo looking forward to Kaley!
April 25th, 2009 10:18 AM
I looked forward to Kaley!
April 25th, 2009 5:04 PM
i think she is izzie's half sister and she is in remission and came to give izzie hope.
April 25th, 2009 5:32 PM
Maybe she is Arizona's sister? Or an old girlfriend of Arizona?
April 26th, 2009 8:30 PM
maybe she is alex's sister. i mean we dont really know that much about alex so maybe he has a sister who comes down to meet izzie or come to her brothers wedding.
or she could possibly be dereks sister.... i dont know
April 27th, 2009 4:58 AM
Please could someone tell me how old these actresses are, cos their age maybe a clue