The Grey's Anatomy Couples Watch

Real-life couples, that is.

According to People magazine, a number of our favorite Grey's Anatomy cast members were spotted out with each other - and their significant others - over the weekend.

Ellen Pompeo threw her husband of over a year now, Chris Ivery, a 41st birthday bash at ONE Sunset in Los Angeles. The lucky guests - such as her Grey's Anatomy costar Eric Dane and his wife Rebecca Gayheart - feasted on the chef's choice tasting menu, which included Maine sea scallops, chestnut tortelloni and truffle mac 'n' cheese.

Following that, it was time for dessert and another treat: "They sang "Happy Birthday" and Chris smiled through the whole song," says an onlooker. "He and Ellen were really cute together, she wanted to him to have fun and enjoy his birthday."

Meanwhile, another of Pompeo's Grey's Anatomy co-stars, Katherine Heigl, and husband Josh Kelley, "smiling from ear to ear" during a romantic dinner at Kabuki in Hollywood.

The happy duo shared sushi during their late-night dinner and enjoyed each other's company, an onlooker says. Always good to hear things are going well for all of them.